Herbal - Synthetic Drug Interactions

Kintoko Kintoko(1), Aghnia Nabila Ananda(2), Anisa Rifka Ridho(3), Annisa Camellia Makati(4), Asti Afrida Yanti(5), Dina Wahyuni(6), Yolanda Sajjida Maghfirah(7), Isnaini Isnaini(8*)


(1) Faculty of Pharmacy University of Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia
(2) Faculty of medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(3) Faculty of medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(4) Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(5) Faculty of medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(6) Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(7) Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(8) [Scopus ID: 57204801189] FK Universitas Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
(*) Corresponding Author

Abstract


Background:  Herbal medicine is currently one of the therapeutic options chosen by the community because it is considered relatively safer and has minimal side effects. Not only used as a single drug, but herbal ingredients can also be combined with synthetic drugs. However, using herbal and synthetic drugs simultaneously can cause a variety of interactions, including synergism, antagonism, and additive effects (potentiation).

Objective: Therefore, it is crucial to do a literature study on the reaction of various herbal medicines to unwanted synthetic drugs to prevent the adverse effects that can be caused.

Methods: The literature review is processed based on academic journals published on NCBI, PubMed, and online journal sources that discuss the interactions between herbal medicines and synthetic drugs from 1997 to 2022.

Results: Herbal drug interactions can be avoided or managed by providing correct patient advice based on reliable information.

Conclusion:The main basic principles of administering these medicines include the doctor's full awareness of the effects and interactions between herbal medicines and herbal medicines and herbal medicines with synthetic drugs.

 


Keywords


herbal medicine; synthetic drug; drug interaction

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References


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DOI: https://doi.org/10.26714/magnamed.10.2.2023.211-220

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