![一般社団法人全国医学部国際交流協議会[J-MICA (Japanese Medical University International Collaborative Assembly)]](http://kokusaikouryu.net/img/banner01.png)
The Effectiveness Of Salicylic acid Therapy In Mild and Moderate Acne Vulgaris
(1) FK Universitas Muhammadiyah Surakarta, Surakarta, Central Java, Indonesia
(2) FK Universitas Muhammadiyah Surakarta, Surakarta, Central Java, Indonesia
(3) FK Universitas Muhammadiyah Surakarta, Surakarta, Central Java, Indonesia
(4) FK Universitas Muhammadiyah Surakarta, Surakarta, Central Java, Indonesia
(*) Corresponding Author
Abstract
Background: Acne vulgaris is a chronic inflammatory disease of polysebaceous follicles characterized by lesions that include blackheads, papules, pustules, nodules, and cysts. The prevalence of acne vulgaris is most significant among adolescents aged 15 to 18. In mild and moderate acne vulgaris, topical treatment enhances skin conditions. It is believed that the ability of salicylic acid to reach the stratum corneum, which exfoliates due to its comedolytic properties, aids in the healing of acne vulgaris.
Objective: Evaluate the efficacy of salicylic acid as a treatment for mild and moderate acne vulgaris.
Methods: This study's design involved a literature search using the terms acne vulgaris and salicylic acid in Google Scholar, PubMed, and Science Direct.
Results: The investigation found 108 articles were discovered and excluded based on the restriction criteria; 8 articles were reviewed. Salicylic acid substantially improved mild and moderate acne, according to all studies. Improvement was measured based on the lesion's severity, the lesion type, and Goodman's qualitative global scarring grading system. There is an improvement in inflammatory, non-inflammatory, and hyperpigmented lesions.
Conclusion: Salicylic acid is clinically beneficial for mild to moderate acne vulgaris.Keywords
Full Text:
PDFReferences
Zheng Y, Yin S, Xia Y, Chen J, Ye C, Zeng Q, et al. Efficacy and safety of 2% supramolecular salicylic acid compared with 5% benzoyl peroxide/0.1% adapalene in the acne treatment: a randomized, split-face, open-label, single-center study. Cutan Ocul Toxicol. 2019;38(1):48–54.
Lu J, Cong T, Wen X, Li X, Du D, He G, et al. Salicylic acid treats acne vulgaris by suppressing AMPK/SREBP1 pathway in sebocytes. Exp Dermatol. 2019;28(7):786–94.
Hadisoebroto G, Budiman S. Determination of Salicylic Acid in Anti Acne Cream which Circulated Around Bandung City Using Ultra Violet Spectrophotometry Method. J Kartika Kim. 2019;2(1):51–6.
Lekakh O, Mahoney AM, Novice K, Kamalpour J, Sadeghian A, Mondo D, et al. Treatment of acne vulgaris with salicylic acid chemical peel and pulsed dye laser: A split face, rater-blinded, randomized controlled trial. J Lasers Med Sci. 2015;6(4):167–70.
Nestor MS, Macri A, Nicole S, Manway M, Paparone P. Efficacy and Tolerability of Over the Counter Light Therapy Mask. Clin Asthetics Dermatology . 2016;9(3):25–35.
Ariyawati A, Chen Y, Pu Y, Zhang Y, Zhang L, Shao X, et al. Efficacy of Supramolecular Salicylic Acid 30% Combined with Intense Pulsed Light Compare to Monotherapy Supramolecular Salicylic Acid 30% in Acne Vulgaris Patients. Open Dermatol J. 2023;17(1):1–8.
Zhang J, Lin P, Guo C, Ma C, Liu Y, Wang Y, et al. Effects and safety of fire needle adjuvant chemical peels therapy in acne vulgaris: a systematic review and meta-analysis. J Dermatolog Treat. 2023;34(1).
Saxena V, Yadav K. Glycolic Acid, Lactic Acid, Mandelic Acid, Salicylic Acid, Citric Acid, Gluconolactone: Skin Exfoliators in Combination Therapy of Acne Vulgaris. Int J Res Eng Sci Manag. 2020;3(10):54–5.
Abdel Meguid AM, Abd Elaziz Ahmed Attallah D, Omar H. Trichloroacetic acid versus salicylic acid in the treatment of acne vulgaris in dark-skinned patients. Dermatologic Surg. 2015;41(12):1398–404.
Alba MN, Gerenutti M, Yoshida VMH, Grotto D. Clinical comparison of salicylic acid peel and LED-Laser phototherapy for the treatment of Acne vulgaris in teenagers. J Cosmet Laser Ther. 2017;19(1):49–53.
Dayal S, Amrani A, Sahu P, Jain VK. Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. J Cosmet Dermatol. 2017;16(1):43–51.
Abdel Hay R, Hegazy R, Abdel Hady M, Saleh N. Clinical and dermoscopic evaluation of combined (salicylic acid 20% and azelaic acid 20%) versus trichloroacetic acid 25% chemical peel in acne: an RCT. J Dermatolog Treat. 2019;30(6):572–7.
Bae BG, Park CO, Shin H, Lee SH, Lee YS, Lee SJ, et al. Salicylic acid peels versus Jessner's solution for acne vulgaris: A comparative study. Dermatologic Surg. 2013;39(2):248–53.
Dayal S, Kalra KD, Sahu P. Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris. J Cosmet Dermatol. 2020;19(2):393–9.
Rafique S, Abaidullah M, Saeed M, Shahzad A, Muqeet N, Hamid H. Clinical efficacy of salicylic acid (20%) and glycolic acid (35%) peel in post acne scarring; randomized controlled trials. Lat Am J Pharm. 2020;39(6):1139–43.
How KN, Lim PY, Wan Ahmad Kammal WSL, Shamsudin N. Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. Int J Dermatol. 2020;59(7):804–12.
Pavithra S, Gopalakrishnan K, Shanmugam J. Efficacy of 70% Glycolic Acid Peel versus 30% Salicylic Acid Peel in the Treatment of Mild to Moderate Acne Vulgaris: A Retrospective Study. J Clin Diagnostic Res. 2022;5–8.
Wacewicz-Muczyńska M, Jankowska K, Leszczyńska K. The effectiveness of Jessner's solution in combination with retinol in reducing acne lesions - a pilot study. Aesthetic Cosmetol Med. 2022;11(5):167–71.
Anicescu MC, Dinu-Pîrvu CE, Talianu MT, Ghica MV, Anuța V, Prisada RM, et al. Insights from a Box–Behnken Optimization Study of Microemulsions with Salicylic Acid for Acne Therapy. Pharmaceutics. 2022;14(1).
Jartarkar S, Gangadhar B, Mallikarjun M, Manjunath P. A randomized, single-blind, active controlled study to compare the efficacy of salicylic acid and mandelic acid chemical peel in the treatment of mild to moderately severe acne vulgaris. Clin Dermatology Rev. 2017;1(1):15.
Boen M, Jacob C. A Review and Update of Treatment Options Using the Acne Scar Classification System. Dermatologic Surg. 2019;45(3):411–22.
Kar B, Panda M, Tripathy S. Comparative study of oral isotretinoin versus oral isotretinoin + 20% salicylic acid peel in the treatment of Active Acne. J Cutan Aesthet Surg. 2013;6(4):204.
Круглова ЛС, Kruglova LS. Вопросы терапии поствоспалительной гиперпигментации постакне Issues of therapy for post-acne post-inflammatory hyperpigmentation. 2022;16(13):11–6.
ElRefaei AM, Abdel Salam HA, Sorour NE. Salicylic-mandelic acid versus glycolic acid peels in Egyptian patients with acne vulgaris. J Egypt Women's Dermatologic Soc. 2015;12(3):196–202.
Khunger N, Chanana C. A perspective on what's new in chemical peels. Cosmoderma. 2022;2:14.
Article Metrics
Abstract view : 331 timesPDF - 88 times
DOI: https://doi.org/10.26714/magnamed.11.1.2024.71-82
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Indexed by
MAGNA MEDIKA by APKKM is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.