The Impact of Blood Glucose Levels on Acid-Fast Bacteria Conversion in Tuberculosis Patients with Diabetes Mellitus

Shahrul Rahman(1*), Andhyka Libawardana Pulungan(2), Kebba S. Bojang(3)

(1) [Scopus ID: 57220181149] FK UMSU, Medan
(2) Universitas Muhammadiyah Sumatera Utara
(3) School of Medicine And Alllied Health Sciences, University of The Gambia, The Gambia
(*) Corresponding Author


Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Pulmonary tuberculosis in DM sufferers will aggravate hyperglycemia and spur ketoacidosis.

Objective: To determine the effect of blood glucose levels on the conversion of acid-fast bacteria (AFB) in TB patients with DM

Methods: This research is descriptive-analytical with a retrospective cohort approach. The data are taken as data from TB patients with DM at the Pulmonary Hospital of North Sumatera Province from July 2018-September 2019. The sample is pulmonary tuberculosis-positive AFB patients with high blood glucose levels, which was carried out with total sampling. The sample used in the study was 49 patients who met the inclusion criteria.

Results: There was that in the category of increased blood glucose levels with AFB converted by 4 (7.3%) respondents, while those who were not converted were 6 (2.7%) respondents. The category of decreased blood glucose levels with AFB was converted by 32 (28.7%) respondents, while 7 (10.3%) respondents were not converted. The p-value shows 0.014, which means the effect of blood glucose on the conversion of acid-fast bacteria has a significant relationship.

Conclusion:There is a significant relationship between the effect of blood glucose levels on acid-fast bacteria conversion.


Blood Glucose Levels; Tuberculosis; AFB; Diabetes Mellitus

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