Basal Cell Carcinoma

Ali Mustofa(1*), Tri Rosalia Nur Sholikah(2), Tapi Singgar Niari(3), Yuli Wahyu Rahmawati(4)

(1) Muhammadiyah Surabaya University
(2) Muhammadiyah Surabaya University
(3) RS Soegiri Lamongan
(4) Muhammadiyah Surabaya University
(*) Corresponding Author


Background: Basal Cell Carcinoma (BCC) is a malignant neoplasm of non-keratinized cells in the basal layer of the epidermis, which is locally invasive, aggressive, destructive, and rarely metastasizes. BCC more commonly occurs in the elderly. Exposure to ultraviolet (UV) rays is the main risk factor for BCC, so predilection is areas of the body that are exposed to UV rays, especially the face, ears, and neck.

Case presentation: The following is a case report of a 65-year-old female patient who works as a farmer. The patient was diagnosed with basal cell carcinoma (BCC) with complaints of black nodules on the face, itching, and bleeding easily. With Dermatological status obtained. The lesion ad regio Fascialis Dextra shows a solitary hyperpigmented nodule, nummular in size, well-circumscribed, and unilateral.

Conclusion:Basal cell carcinoma is a malignant skin tumor originating from non-keratinizing cells in the basal layer of the epidermis.



Carcinoma of Skin, Basal Cell Carcinoma, Ultraviolet

Full Text:



Mohan S V., Chang ALS. Advanced Basal Cell Carcinoma: Epidemiology and Therapeutic Innovations. Curr Dermatol Rep. 2014;3(1):40–5.

Diem E. Basalioma. Ther Umsch. 2013;5(3):21–6.

Combalia, Andrea and Cristina Carrera. 2020. Squamous Cell Carcinoma: An Update on Diagnosis and treatment. Dermatology Practical & Conceptual. 2020;10 (3):e2020066

Tan, Tansil Sukmawati and Gabriela Reginata. 2015. Diagnosis dan tatalaksana Karsinoma Sel Basal. Jakarta: Tarumanegara university. continuing medical education CDK-235/vol. 42 no. 12, th 2015

Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, Kerl H. Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol. 2007 Dec;157 Suppl 2:47-51. doi: 10.1111/j.1365-2133.2007.08273.x. PMID: 18067632.

Marzuka AG, Book SE. Basal cell carcinoma: Pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale J Biol Med. 2015;88(2):167–79.

Fania L, Didona D, Morese R, Campana I, Coco V, Di Pietro FR, et al. Basal cell carcinoma: From pathophysiology to novel therapeutic approaches. Biomedicines. 2020;8(11):1–38.

TAN ST, GHAZNAWIE M, REGINATA G. Deteksi Dini Karsinoma Sel Basal. Indones J Cancer. 2016;10(2):61.

Dika E, Scarfì F, Ferracin M, Broseghini E, Marcelli E, Bortolani B, et al. Basal cell carcinoma: A comprehensive review. Int J Mol Sci. 2020;21(15):1–11.

Seidl-Philipp M, Frischhut N, Höllweger N, Schmuth M, Nguyen VA. Known and new facts on basal cell carcinoma. JDDG - J Ger Soc Dermatology. 2021;19(7):1021–41.

Bakshi, Anshika, Sandeep C. Chaudhary, Mentab Rana, Craig A. Elmets, Mohammad Athar. 2017. Basal Cell Carcinoma pathogenesis and therapy involving hedgehog signalling and beyond. Molecular Carcinogensisis Vol. 56, Issue 12.

McDaniel B, Badri T, Steele RB. Basal Cell Carcinoma. [Updated 2021 Sep 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan

Fakhrosa, Irma. Eva Krishna S. Jono Hadi Agusni, Vina Feriza, Nia Ayu Saraswati. 2018. Manifestasi Klinis dan Gambaran Dermoskopi pada Karsinoma Sel Basal. Syifa’ Medika, Vol. 8 (No.2), Maret 2018

Totonchy M, Leffell D. Emerging concepts and recent advances in basal cell carcinoma. F1000Research. 2017;6(0):2–11.

Kasumagic-Halilovic E, Hasic M, Ovcina-Kurtovic N. A Clinical Study of Basal Cell Carcinoma. Med Arch (Sarajevo, Bosnia Herzegovina). 2019;73(6):394–8.

Kim DP, Kus KJB, Ruiz E. Basal Cell Carcinoma Review. Hematol Oncol Clin North Am. 2019;33(1):13–24.

Piva De Freitas P, Senna CG, Tabai M, Chone CT, Altemani A. Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease. Case Rep Med. 2017;2017:4–7.

Santoso A, Darmaputra IGN, Gotama D, Sissy S. Terapi pada karsinoma sel basal. Intisari Sains Medis. 2021;12(2):723.

Tanese K. Diagnosis and management of basal cell carcinoma. Curr Treat Options Oncol. 2019;20(2).

Fagan J, Brooks J, Ramsey ML. Basal Cell Cancer. [Updated 2022 Mar 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.

Article Metrics

Abstract view : 267 times
PDF - 187 times



  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Indexed by




Creative Commons License

MAGNA MEDIKA by APKKM is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.