Gambaran Kelainan Cardiovascular pada Pasien Schizophrenia: Literature Review

Agustina Ika Wulandari(1*), Arum Pratiwi(2)


(1) Program Studi Keperawatan, Universitas Muhammadiyah Surakarta
(2) Program Studi Keperawatan, Universitas Muhammadiyah Surakarta
(*) Corresponding Author

Abstract


Kelainan kardiovakular merupakan penyebab utama kecacatan dan kematian dini di seluruh dunia, dan berkontribusi besar terhadap meningkatnya biaya perawatan kesehatan, bahkan dua sampai tiga kali lipat serta mengakibatkan penurunan harapan hidup pada pasien schizophrenia. Banyak sekali kelainan atau penyakit cardiovascular yang menyertai pasien schizophrenia. Ulasan artikel ini berfokus pada kelainan cardiovascular pada pasien schizophrenia. Tujuan literature review ini untuk mengidentifikasi dan merangkum artikel-artikel terkait gambaran kelainan cardiovascular pada pasien schizophrenia. Penelitian ini menggunakan metode studi literature (literature review) dengan basis data utama dalam pencarian yaitu Pubmed, Elsevier, Google Schoolar dalam jangka waktu terbit tahun 2015-2021. Artikel yang di analisis dalam penelitian berjumlah 11 artikel. Hasil penelitian menunjukkan kematian pada kelainan cardiovaskular pada pasien schizophrenia sangat tinggi dibandingkan dengan populasi schizophrenia pada umumnya (tanpa ada komorbiditas penyakit kardiovaskular). Penyakit Jantung Koroner merupakan prevalensi tertinggi kelainan cardiovascular pada pasien schizophrenia. Pada pasien schizophrenia terdapat perubahan pada bentuk dan fungsi dari jantung atau sistem kardiovaskular. Perubahan tersebut disebabkan oleh faktor risiko dan diperparah oleh obat antipsikotik, serta pengobatan kardiovaskular yang dikesampingkan.


Keywords


kelainan kardiovaskular; penyakit mental; skizofrenia

Full Text:

PDF

References


Al-Seddik, G., Hachem, D., Haddad, C., Hallit, S., Salameh, P., Nabout, R., & Zoghbi, M. (2019). Cardiovascular events in hospitalised patients with schizophrenia: a survival analysis. International Journal of Psychiatry in Clinical Practice, 23(2), 106–113. https://doi.org/10.1080/13651501.2018.1545910

Attar, R., Valentin, J. B., Freeman, P., Andell, P., Aagaard, J., & Jensen, S. E. (2019). The effect of schizophrenia on major adverse cardiac events, length of hospital stay, and prevalence of somatic comorbidities following acute coronary syndrome. European Heart Journal - Quality of Care and Clinical Outcomes, 5(2), 121–126. https://doi.org/10.1093/ehjqcco/qcy055

Azad, M. C., Shoesmith, W. D., Al Mamun, M., Abdullah, A. F., Naing, D. K. S., Phanindranath, M., & Turin, T. C. (2016). Cardiovascular diseases among patients with schizophrenia. In Asian Journal of Psychiatry (Vol. 19, Issue 2016, pp. 28–36). Elsevier B.V. https://doi.org/10.1016/j.ajp.2015.11.012

Bär, K. J. (2015). Cardiac autonomic dysfunction in patients with schizophrenia and their healthy relatives - a small review. Frontiers in Neurology, 6(JUN), 1–6. https://doi.org/10.3389/fneur.2015.00139

Brobakken, M. F., Nygård, M., Taylor, J. L., Güzey, I. C., Morken, G., Reitan, S. K., Heggelund, J., Vedul-Kjelsaas, E., & Wang, E. (2019). A comprehensive cardiovascular disease risk profile in patients with schizophrenia. Scandinavian Journal of Medicine and Science in Sports, 29(4), 575–585. https://doi.org/10.1111/sms.13371

Correll, C. U., Solmi, M., Veronese, N., Bortolato, B., Rosson, S., Santonastaso, P., Thapa-Chhetri, N., Fornaro, M., Gallicchio, D., Collantoni, E., Pigato, G., Favaro, A., Monaco, F., Kohler, C., Vancampfort, D., Ward, P. B., Gaughran, F., Carvalho, A. F., & Stubbs, B. (2017). Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls. World Psychiatry, 16(2), 163–180. https://doi.org/10.1002/wps.20420

Emul, M., & Kalelioglu, T. (2015). Etiology of cardiovascular disease in patients with schizophrenia: Current perspectives. Neuropsychiatric Disease and Treatment, 11, 2493–2503. https://doi.org/10.2147/NDT.S50006

Heiberg, I. H., Jacobsen, B. K., Balteskard, L., Bramness, J. G., Næss, Ystrom, E., Reichborn-Kjennerud, T., Hultman, C. M., Nesvåg, R., & Høye, A. (2019). Undiagnosed cardiovascular disease prior to cardiovascular death in individuals with severe mental illness. Acta Psychiatrica Scandinavica, 139(6), 558–571. https://doi.org/10.1111/acps.13017

Hert, M. De, Detraux, J., & Vancampfort, D. (2018). Tr a n s l a t i o n a l r e s e a r c h. 31–40.

Holt, R. I. G. (2015). Cardiovascular disease and severe mental illness. Key Issues in Mental Health, 179, 54–65. https://doi.org/10.1159/000365531

Howell, S., Yarovova, E., Khwanda, A., & Rosen, S. D. (2019). Cardiovascular effects of psychotic illnesses and antipsychotic therapy. In Heart (Vol. 105, Issue 24, pp. 1852–1859). BMJ Publishing Group. https://doi.org/10.1136/heartjnl-2017-312107

Ignaszewski, M. J., Yip, A., & Fitzpatrick, S. (2015). Schizophrenia and. may, 154–157.

Kilicaslan, E. E., Karakilic, M., & Erol, A. (2019). The relationship between 10 years risk of cardiovascular disease and schizophrenia symptoms: Preliminary results. Psychiatry Investigation, 16(12), 933–939. https://doi.org/10.30773/pi.2019.0063

Kritharides, L., Chow, V., & Lambert, T. J. R. (2017). Cardiovascular disease in patients with schizophrenia. Medical Journal of Australia, 206(2), 91–95. https://doi.org/10.5694/MJA16.00650

Madewell, Z. J., Yang, Y., Jr, I. M. L., Halloran, M. E., & Dean, N. E. (2020). NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice. 1. MedRxiv, 165, 1–13.

Osimo, E. F., Brugger, S. P., De Marvao, A., Pillinger, T., Whitehurst, T., Statton, B., Quinlan, M., Berry, A., Cook, S. A., O’Regan, D. P., & Howes, O. D. (2020). Cardiac structure and function in schizophrenia: Cardiac magnetic resonance imaging study. British Journal of Psychiatry, 217(2), 450–457. https://doi.org/10.1192/bjp.2019.268

Pillinger, T., Osimo, E. F., de Marvao, A., Berry, M. A., Whitehurst, T., Statton, B., Quinlan, M., Brugger, S., Vazir, A., Cook, S. A., O’Regan, D. P., & Howes, O. D. (2019). Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study. Translational Psychiatry, 9(1). https://doi.org/10.1038/s41398-019-0502-x

Riset Kesehatan Dasar (Riskesdas). (2018). Badan Penelitian dan Pengembangan Kesehatan Kementerian RI tahun 2018.

Søgaard, M., Skjøth, F., Kjældgaard, J. N., Larsen, T. B., Hjortshøj, S. P., & Riahi, S. (2017). Atrial fibrillation in patients with severe mental disorders and the risk of stroke, fatal thromboembolic events and bleeding: A nationwide cohort study. BMJ Open, 7(12), 1–9. https://doi.org/10.1136/bmjopen-2017-018209

Westman, J., Eriksson, S. V., Gissler, M., Hällgren, J., Prieto, M. L., Bobo, W. V., Frye, M. A., Erlinge, D., Alfredsson, L., & Ösby, U. (2018). Increased cardiovascular mortality in people with schizophrenia: A 24-year national register study. Epidemiology and Psychiatric Sciences, 27(5), 519–527. https://doi.org/10.1017/S2045796017000166

World Health Organization. (2007). Prevention of cardiovascular disease: guidelines for assessment and management of total cardiovascular risk. World Health Organization.

______________________. (2019). WHO Schizophrenia. Diakses dari https://www.who.int/news-room/fact-sheets/detail/schizophrenia

Wu, S. I., Chen, S. C., Liu, S. I., Sun, F. J., Juang, J. J. M., Lee, H. C., Kao, K. L., Dewey, M. E., Prince, M., Stewart, R., & Van Winkel, R. (2015). Relative risk of acute myocardial infarction in people with schizophrenia and bipolar disorder: A population-based cohort study. PLoS ONE, 10(8), 1–14. https://doi.org/10.1371/journal.pone.0134763


Article Metrics

Abstract view : 202 times
PDF - 215 times

DOI: https://doi.org/10.26714/jkj.10.2.2022.307-316

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

View My Stats

PPNI Univ. Muhammadiyah Semarang

Jl. Kedungmundu Raya No. 18 Semarang Gedung NRC University of Muhammadiyah Semarang

Phone: 02476740287
Fax: 02476740287
Email: [email protected]

 

This work is licensed under a Creative Commons Attribution 4.0 International License.